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Understanding Dihydrotestosterone (DHT): The Hormone and Its Impact

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Dihydrotestosterone (DHT) is a hormone derived from testosterone, playing a critical role in the development and maintenance of male characteristics. Despite its importance, DHT is often associated with various health issues, particularly hair loss and prostate problems. This article delves into what DHT is, how it is produced, its physiological roles, and why its levels matter. What is DHT? DHT, or dihydrotestosterone, is an androgen, which is a type of sex hormone. It is a derivative of testosterone, created through the action of the enzyme 5-alpha-reductase. This enzyme converts testosterone into DHT in certain tissues, including the skin, liver, prostate, and hair follicles. Production and Conversion The process of converting testosterone to DHT involves 5-alpha-reductase enzymes (types 1 and 2). Type 1 is primarily found in the skin and liver, while type 2 is mainly in the prostate and hair follicles. This conversion is a key step in the amplification of androgenic act